The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Thoracic epidural or spinal hematoma
Publications
Anti-coagulation Drug Warfarin Contributes to Severe Adverse Outcomes in Prolonged Unsupervised Use: A Double-edged Sword.
Cureus 2018 Sep 22;10;e3347 — 2018 Sep 22 — e3347
Warfarin-associated Intraspinal Hematoma.
The Keio journal of medicine 2016 Dec 25;65;74-77 — 2016 Dec 25 — 74-77
Epidural Hematoma Treated Conservatively: When to Expect the Worst.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2016 Jan;43;74-81 — 2016 Jan — 74-81