The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Path: Pulmonary fibrosis (UIP-pattern)
See also under PMID 4827629
Publications
Pulmonary fibrosis following long-term nitrofurantoin therapy.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1982 May 08;61;714-7 — 1982 May 08 — 714-7
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 22-1974.
The New England journal of medicine 1974 Jun 06;290;1309-14 — 1974 Jun 06 — 1309-14