The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Hematoma of/around central airway wall potentially causing UAO
Publications
Upper airway hematoma: An unusual presentation of acute upper airway obstruction.
Respiratory medicine case reports 2022;36;101612 — 2022 — 101612
Images in Clinical Medicine. Spontaneous Retropharyngeal Hematoma.
The New England journal of medicine 2016 Jan 21;374;e3 — 2016 Jan 21 — e3
Warfarin induced sublingual hematoma: a Ludwig angina mimic.
American journal of otolaryngology 2015 Jan-Feb;36;84-6 — 2015 Jan-Feb — 84-6
Massive sublingual hematoma secondary to anticoagulant therapy complicated by a traumatic denture: a case report.
Journal of medical case reports 2012 Apr 10;6;105 — 2012 Apr 10 — 105
Images in clinical medicine. Lingual hematoma after thrombolytic therapy.
The New England journal of medicine 2011 Feb 17;364;e13 — 2011 Feb 17 — e13
[Sublingual haematoma: an unusual complication of oral anticoagulation therapy: about one case].
Annales francaises d'anesthesie et de reanimation 2008 Jan;27;94-6 — 2008 Jan — 94-6
Upper airway obstruction by sublingual hematoma: a complication of anticoagulation therapy with acenocoumarol.
American journal of otolaryngology 2006 Mar-Apr;27;129-32 — 2006 Mar-Apr — 129-32
Case of sublingual hematoma threatening airway obstruction.
Medical science monitor : international medical journal of experimental and clinical research 2003 Nov;9;CS95-7 — 2003 Nov — CS95-7
[Dyspnea caused by spontaneous hematoma of the oropharynx and larynx during marcumar therapy].
HNO 2001 Mar;49;220-3 — 2001 Mar — 220-3
Coumadin-induced lingual hemorrhage mimicking angioedema.
The American journal of medicine 2000 Jul;109;77-8 — 2000 Jul — 77-8
[Upper airway obstruction--a rare complication after anti-coagulant therapy].
Harefuah 1993 Mar 15;124;336-8, 391 — 1993 Mar 15 — 336-8, 391
Unusual complications in the course of anticoagulant therapy.
The American journal of medicine 1969 Mar;46;460-3 — 1969 Mar — 460-3
Upper-airway obstruction as a complication of oral anticoagulation therapy.
Critical care medicine 1986 Sep;14;830-1 — 1986 Sep — 830-1
Upper airway obstruction secondary to warfarin-induced sublingual hematoma.
Archives of otolaryngology--head & neck surgery 1989 Jun;115;718-20 — 1989 Jun — 718-20
[Spontaneous mediastinal hematoma during therapy with oral anticoagulants].
Giornale italiano di cardiologia 1990 Oct;20;972-5 — 1990 Oct — 972-5
Upper airway obstruction induced by warfarin sodium.
Archives of otolaryngology (Chicago, Ill. : 1960) 1976 Aug;102;505-6 — 1976 Aug — 505-6
Upper airway obstruction as a complication of oral anticoagulation therapy. Report of three cases.
Archives of internal medicine 1979 Oct;139;1151-3 — 1979 Oct — 1151-3