The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLII.a

Alveolar hemorrhage (AH), diffuse AH (DAH)

Publications

Olmos V, López CM

Brodifacoum poisoning with toxicokinetic data.

Clinical toxicology (Philadelphia, Pa.) 2007 Jun-Aug;45;487-9 — 2007 Jun-Aug — 487-9

Waien SA, Hayes D, Leonardo JM

Severe coagulopathy as a consequence of smoking crack cocaine laced with rodenticide.

The New England journal of medicine 2001 Aug 30;345;700-1 — 2001 Aug 30 — 700-1

Palmer RB, Alakija P, de Baca JE, Nolte KB

Fatal brodifacoum rodenticide poisoning: autopsy and toxicologic findings.

Journal of forensic sciences 1999 Jul;44;851-5 — 1999 Jul — 851-5

Chua JD, Friedenberg WR

Superwarfarin poisoning.

Archives of internal medicine 1998 Sep 28;158;1929-32 — 1998 Sep 28 — 1929-32

La Rosa FG, Clarke SH, Lefkowitz JB

Brodifacoum intoxication with marijuana smoking.

Archives of pathology & laboratory medicine 1997 Jan;121;67-9 — 1997 Jan — 67-9

Barnett VT, Bergmann F, Humphrey H, Chediak J

Diffuse alveolar hemorrhage secondary to superwarfarin ingestion.

Chest 1992 Oct;102;1301-2 — 1992 Oct — 1301-2