The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Hemopericardium - Bloody pericardial effusion
Publications
Heparin-induced cardiac tamponade and life-threatening hyperkalema in a patient with chronic hemodialysis.
The Kaohsiung journal of medical sciences. 2005;21(3):128-33
Cardiac tamponade secondary to hemorrhagic pericarditis during continuous hemofiltration for renal failure. The role of the anticoagulant.
Renal failure. 1994;16(2):299-301
Fatal cardiac tamponade in systemic lupus erythematosus--a hazard of anticoagulation.
American heart journal. 1990;119(2 Pt 1):422-3