The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.b

Pneumonitis (interstitial lung disease/ILD)

Publications

Phalex EM, Mbina Nzienghi D, Nabil L, Mouina N, Ouhadi M

When Clopidogrel Reaches the Lung: A Case of Diffuse Interstitial Lung Disease.

Cureus. 2026;18(7):e112287

An J, Lee SH, Chang B

Clopidogrel-Induced Interstitial Lung Disease: A Case Report.

Therapeutics and clinical risk management. 2021;17:711-715

Tomoda Y, Miyajima T, Nagasawa C, Awaya Y

Clopidogrel-induced pneumonia.

BMJ case reports. 2021;14(6)

Tamagaki G, Matsushita H, Suzumura T, Watanabe T, Yamada S, Hirata K

[A case of drug-induced pneumonia caused by clopidogrel].

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society. 2010;48(5):404-8