Philippe Camus, M.D.

Dijon, France

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X.u

X - Systemic/Distant conditions, syndromes and reactions

Vasculitis, pulmonary (w/wo AH), extrapulmonary, systemic: ANCA-positive

Last update 20/02/2022

Drug-induced ANCA-associated or related systemic disease (formerly known as Wegener's) may manifest with vasculitis in almost any organ, arthritis, skin, kidney, lung (usually in the form of DAH) or other end-organ involvement mimicking idiopathic ANCA-related granulomatosis and polyangiitis (Wegener) or PAN. ANCA titers can be very high and multispecific, decreasing upon drug discontinuance paralleling clinical improvement. Treatment approach in severe cases is similar to primary ANCA disease. See under IIId, VId, Xm and at PMID 21674413. ANCA specificity for cocaine and levamisole at PMID 21654271. Early cases at a time ANCA were not described may be found under Xm. Reviews at PMID 19335842, 24485158

Causative drugs

41

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Adalimumab
I.a
I.b
I.c
I.e
I.g
I.n
I.x
I.aa
II.e
III.a
III.d
IV.a
VI.d
VI.m
IX.j
X.b
X.d
X.e
X.l
X.m
X.u
XII.a
XII.s
XVI.e
XVI.k
XIX.a
XIX.d
XIX.f
XX.a
XX.b
XX.c
XX.e
XX.f
XX.g
XX.y
XX.z
Allopurinol
V.a
VII.d
X.a
X.o
X.p
X.u
XIX.ay
Antibiotics
I.a
I.c
I.d
IV.a
IV.b
V.a
X.a
X.f
X.u
XI.l
XII.c
Antithyroid drugs
X.e
X.u
XI.l
Atorvastatin
I.a
I.e
VI.a
X.d
X.u
X.aa
Benzylthiouracil
I.a
III.b
III.d
VII.d
X.u
Bevacizumab
I.a
II.e
III.a
III.c
III.g
III.h
III.k
IV.a
V.m
V.s
V.ab
VI.f
VII.a
VII.b
X.f
X.u
XI.t
XII.a
XII.f
XII.g
XII.h
XII.ak
XII.al
XII.av
XIII.f
XVI.ac
XVI.ad
XVI.bh
Breast implants - Augmentation mammaplasty (w/wo evidence for leakage/rupture)
I.a
I.c
I.o
I.am
I.an
II.u
III.a
VI.a
VI.w
VI.x
VIII.a
VIII.e
VIII.o
X.e
X.j
X.l
X.m
X.o
X.s
X.u
X.af
XII.c
XVI.k
XVI.ax
XVI.bk
XVII.c
XIX.af
XIX.aj
XIX.bq
XIX.cx
XXI.f
XXI.h
XXI.i
Carbimazole
III.b
III.d
VI.a
VI.b
VII.d
X.o
X.u
Catheter coating
VI.a
VII.g
X.s
X.u
XVI.w
XVI.ac
XVI.ap
XIX.ab
XIX.an
XIX.bk
Clozapine
I.a
I.c
IV.a
V.a
VI.a
VI.b
VI.m
VII.a
IX.f
X.e
X.q
X.u
X.w
XI.h
XI.l
XI.ah
XII.d
XII.g
XII.i
XII.ak
XIX.bu
XIX.cp
Cocaine
I.c
I.d
I.e
I.u
I.aa
II.a
II.b
III.a
III.b
III.c
III.n
IV.a
IV.b
IV.g
V.a
V.c
V.l
V.p
V.q
V.w
V.ai
V.aj
V.al
V.aq
VI.f
VI.ac
VII.a
VII.b
VII.l
VIII.h
IX.k
IX.o
X.f
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X.o
X.q
X.u
X.w
X.z
X.ae
X.af
X.au
XI.b
XI.k
XI.l
XI.o
XI.ab
XI.au
XII.a
XII.f
XII.g
XII.h
XII.n
XII.aa
XII.ag
XII.ah
XII.al
XII.ar
XIV.b
XVI.k
XIX.b
XIX.r
XIX.t
XIX.v
XIX.ac
XIX.cz
XX.b
COVID19 (SARS-CoV2) vaccination/vaccine
I.a
I.b
I.c
I.z
I.ae
I.az
I.bd
II.b
II.e
III.a
III.m
IV.a
IV.c
VII.a
VII.b
VII.ab
IX.r
IX.y
IX.ab
X.b
X.d
X.f
X.h
X.j
X.l
X.o
X.u
X.al
X.bg
X.bh
X.bi
X.bk
XI.b
XII.a
XII.c
XII.d
XII.e
XII.f
XII.h
XII.i
XII.l
XII.n
XII.r
XII.u
XII.ak
XII.bi
XVI.b
XVI.c
XVI.ba
XVIII.a
XVIII.c
XIX.a
XIX.d
Denosumab
I.a
I.z
I.ap
V.a
V.ae
IX.h
IX.z
X.u
Doxycycline
I.a
IV.a
X.d
X.f
X.i
X.q
X.u
XIII.b
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