The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.o

Vascultis (pulmonary, extrathoracic or systemic)-ANCA status unknown or negative)

Publications

Lim D, Rademaker M, Asztely F, Ratnaweera M, Coltman G

Cerebral vasculitis and multi-focal neurological deficits due to allopurinol-induced hypersensitivity syndrome.

The Australasian journal of dermatology 2014 Feb;55;84-7 — 2014 Feb — 84-7

Jarzobski J, Ferry J, Wombolt D, Fitch DM, Egan JD

Vasculitis with allopurinol therapy.

American heart journal 1970 Jan;79;116-21 — 1970 Jan — 116-21