The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XII.c

Pericardial effusion (w/wo tamponade)

Publications

Conte C, Princi G, D'Amario D, Sanna T, Pedicino D, Liuzzo G

Incessant pericarditis following the second dose of SARS-CoV-2 mRNA vaccine successfully treated with anakinra: a case report.

European heart journal. Case reports 2022 Sep;6;ytac357 — 2022 Sep — ytac357

Shen X, Koh MSH, Lim BY, Demo-Os M, Chien JMF, Santosa A, Taha AA

Acute pericarditis and cardiac tamponade after Covid-19 vaccination.

Singapore medical journal 2021 Nov 08;; — 2021 Nov 08

Vidula MK, Ambrose M, Glassberg H, Chokshi N, Chen T, Ferrari VA, Han Y

Myocarditis and Other Cardiovascular Complications of the mRNA-Based COVID-19 Vaccines.

Cureus 2021 Jun;13;e15576 — 2021 Jun — e15576