The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIX.f

Anaphylaxis-Anaphylactoid reaction (can be fatal)

Publications

Teufelberger AR, Dan AR, Irmler L, Wolf P, Kränke B

COVID-19 vaccines: anaphylaxis and anxiety : A case study from an allergy unit.

Wiener klinische Wochenschrift 2024 Nov;136;590-597 — 2024 Nov — 590-597

Luxi N, Giovanazzi A, Arcolaci A, Bonadonna P, Crivellaro MA, Cutroneo PM, Ferrajolo C, Furci F, Guidolin L, Moretti U, Olivieri E, Petrelli G, Zanoni G, Senna G, Trifirò G

Allergic Reactions to COVID-19 Vaccines: Risk Factors, Frequency, Mechanisms and Management.

BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2022 Jul;36;443-458 — 2022 Jul — 443-458

Armstrong L, Maguire N

A Case Report of Prolonged Anaphylaxis after COVID-19 Vaccine.

Clinical practice and cases in emergency medicine 2022 Feb;6;21-24 — 2022 Feb — 21-24

Pitlick MM, Park MA, Gonzalez-Estrada A, Chiarella SE

Biphasic anaphylaxis after first dose of messenger RNA coronavirus disease 2019 vaccine with positive polysorbate 80 skin testing result.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2021 Jul 31;; — 2021 Jul 31

Tanno LK, Castells M, Caminati M, Senna G, Demoly P

Anaphylaxis and Coronavirus Disease 2019 vaccine: a danger relationship?

Current opinion in allergy and clinical immunology 2021 Jul 30;; — 2021 Jul 30

Krantz MS, Liu Y, Phillips EJ, Stone CA

COVID-19 vaccine anaphylaxis: PEG or not?

Allergy 2021 06;76;1934-1937 — 2021 06 — 1934-1937

Bellomo RG, Gallenga CE, Caraffa A, Tetè G, Ronconi G, Conti P

Anaphylaxis is a rare reaction in COVID-19 vaccination.

Journal of biological regulators and homeostatic agents 2021 Jun 09;35; — 2021 Jun 09

Sampath V, Rabinowitz G, Shah M, Jain S, Diamant Z, Jesenak M, Rabin R, Vieths S, Agache I, Akdis M, Barber D, Breiteneder H, Chinthrajah S, Chivato T, Collins W, Eiwegger T, Fast K, Fokkens W, O'Hehir RE, Ollert M, O'Mahony L, Palomares O, Pfaar O, Riggi

Vaccines and Allergic reactions: the past, the current COVID-19 pandemic, and future perspectives.

Allergy 2021 Apr 02;; — 2021 Apr 02

Bousquet J, Agache I, Blain H, Jutel M, Ventura MT, Worm M, Del Giacco S, Benetos A, Bilo MB, Czarlewski W, Abdul Latiff AH, Al-Ahmad M, Angier E, Annesi-Maesano I, Atanaskovic-Markovic M, Bachert C, Barbaud A, Bedbrook A, Bennoor KS, Berghea EC, Bindslev

Management of anaphylaxis due to COVID-19 vaccines in the elderly.

Allergy 2021 Apr 02;; — 2021 Apr 02

Cabanillas B, Akdis CA, Novak N

Allergic reactions to the first COVID-19 vaccine: A potential role of polyethylene glycol?

Allergy 2021 06;76;1617-1618 — 2021 06 — 1617-1618