The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XI.b

Chest pain (acute or subacute), lone or prominent

Publications

Singh A, Nguyen L, Everest S, Afzal S, Shim A

Acute Pericarditis Post mRNA-1273 COVID Vaccine Booster.

Cureus. 2022;14(2):e22148

Bengel CP, Kacapor R

A report of two cases of myocarditis following mRNA coronavirus disease 2019 vaccination.

European heart journal. Case reports. 2022;6(1):ytac004

Larson KF, Ammirati E, Adler ED, Cooper LT Jr, Hong KN, Saponara G, Couri D, Cereda A, Procopio A, Cavalotti C, Oliva F, Sanna T, Ciconte VA, Onyango G, Holmes DR, Borgeson DD

Myocarditis After BNT162b2 and mRNA-1273 Vaccination.

Circulation. 2021;144(6):506-508