The Drug-Induced Respiratory Disease Website and App

Breast implants - Augmentation mammaplasty (w/wo evidence for leakage/rupture)

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.q

Systemic inflammatory response

Publications

Kappel RM, Cohen Tervaert JW, Pruijn GJ

Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) due to silicone implant incompatibility syndrome in three sisters.

Clinical and experimental rheumatology. 2014;32(2):256-8

Cohen Tervaert JW, Kappel RM

Silicone implant incompatibility syndrome (SIIS): a frequent cause of ASIA (Shoenfeld's syndrome).

Immunologic research. 2013;56(2-3):293-8

Vera-Lastra O, Medina G, Cruz-Dominguez Mdel P, Jara LJ, Shoenfeld Y

Autoimmune/inflammatory syndrome induced by adjuvants (Shoenfeld's syndrome): clinical and immunological spectrum.

Expert review of clinical immunology. 2013;9(4):361-73

Shoenfeld Y, Agmon-Levin N

'ASIA' - autoimmune/inflammatory syndrome induced by adjuvants.

Journal of autoimmunity. 2011;36(1):4-8