The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Systemic inflammatory response
Publications
Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) due to silicone implant incompatibility syndrome in three sisters.
Clinical and experimental rheumatology 2014 Mar-Apr;32;256-8 — 2014 Mar-Apr — 256-8
Silicone implant incompatibility syndrome (SIIS): a frequent cause of ASIA (Shoenfeld's syndrome).
Immunologic research 2013 Jul;56;293-8 — 2013 Jul — 293-8
Autoimmune/inflammatory syndrome induced by adjuvants (Shoenfeld's syndrome): clinical and immunological spectrum.
Expert review of clinical immunology 2013 Apr;9;361-73 — 2013 Apr — 361-73
'ASIA' - autoimmune/inflammatory syndrome induced by adjuvants.
Journal of autoimmunity 2011 Feb;36;4-8 — 2011 Feb — 4-8