The Drug-Induced Respiratory Disease Website and App

Breast implants - Augmentation mammaplasty (w/wo evidence for leakage/rupture)

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

VII.a

Lymphadenopathy (intrathoracic)

Publications

Banerdt J, Johnson J, Sandler K, Maldonado F, Aboudara M

Silicone Lymphadenopathy after Rupture of Breast Implant.

American journal of respiratory and critical care medicine. 2020;201(11):e77-e78

D'hulst L, Nicolaij D, Beels L, Gheysens O, Alaerts H, Van de Wiele C, Maes A

False-Positive Axillary Lymph Nodes Due to Silicone Adenitis on (18)F-FDG PET/CT in an Oncological Setting.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2016;11(6):e73-5

Caldeira M, Ferreira AC

Siliconosis: autoimmune/inflammatory syndrome induced by adjuvants (ASIA).

The Israel Medical Association journal : IMAJ. 2012;14(2):137-8