The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Autoimmunity-Autoimmune conditions (+ANA, +anti-ds-DNA, +ANCAs, other auto-Abs)
Publications
Two hundreds cases of ASIA syndrome following silicone implants: a comparative study of 30 years and a review of current literature.
Immunologic research 2017 02;65;120-128 — 2017 02 — 120-128
Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) 2013: Unveiling the pathogenic, clinical and diagnostic aspects.
Journal of autoimmunity 2013 Dec;47;1-16 — 2013 Dec — 1-16
Silicone implant incompatibility syndrome (SIIS): a frequent cause of ASIA (Shoenfeld's syndrome).
Immunologic research 2013 Jul;56;293-8 — 2013 Jul — 293-8
Autoimmune/inflammatory syndrome induced by adjuvants (Shoenfeld's syndrome): clinical and immunological spectrum.
Expert review of clinical immunology 2013 Apr;9;361-73 — 2013 Apr — 361-73
A comparison of autoantibody production in asymptomatic and symptomatic women with silicone breast implants.
The Journal of rheumatology 1999 Jan;26 — 1999 Jan — 73-7