The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XX.g

Tuberculosis (pulmonary, pulmonary, extrapulmonary or disseminated). Reactivation or de novo

Publications

Silva M, Braga J, Fernandes C, Ferreira JM, Marques C, Silva CC, Costa CL

Disseminated Tuberculosis Associated With Adalimumab Therapy.

Journal of medical cases 2021 Sep;12;343-346 — 2021 Sep — 343-346

Benchoukroun S, Gaillard S, Vermersch-Langlin A, Deregnaucourt D

Disseminated tuberculosis complicated by immune reconstitution inflammatory syndrome under anti-TNF treatment.

European journal of dermatology : EJD 2020 Jun 01;30;322-323 — 2020 Jun 01 — 322-323

Agudo B, Díaz G, González-Lama Y

Adalimumab-Receiving Ulcerative Colitis Patient Suffered Latent Tuberculosis Reactivation Despite Correct Chemoprophylaxis and was Successfully Treated while on Anti-Tumour Necrosis Factor Therapy.

Journal of Crohn's & colitis 2016 Dec;10;1453-1454 — 2016 Dec — 1453-1454

Assante LR, Barra E, Bocchino M, Zuccarini G, Ferrara G, Sanduzzi A

Tuberculosis of the tongue in a patient with rheumatoid arthritis treated with methotrexate and adalimumab.

Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 2014 Jun;22;144-8 — 2014 Jun — 144-8

Caldera F, Grimes I, Soni A

Reactivation of latent tuberculosis in a Crohn's patient after TB prophylaxis treated with adalimumab.

The American journal of gastroenterology 2013 Jul;108;1181-2 — 2013 Jul — 1181-2

Martínez-Caselles A, Martínez-Pascual C, Muñoz-Tornero M, Sánchez-Torres A, Carballo-Álvarez F

Tuberculous monoarthritis after treatment with adalimumab in Crohn's disease.

Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 2012 Mar;104;157-8 — 2012 Mar — 157-8

Barouta G, Karapetsa M, Kostopoulou E, Alexiou I, Koukoulis G, Sakkas LI

Oral tuberculosis in a patient with rheumatoid arthritis after long treatment with methotrexate and adalimumab.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 2010 Oct;16;330-1 — 2010 Oct — 330-1

Yoo WH

Multiple organ tuberculosis of lung, pleura, and peritoneum in ankylosing spondylitis during adalimumab therapy.

Rheumatology international 2012 Mar;32;787-90 — 2012 Mar — 787-90

Azevedo VF, Parchen C, Coelho SA, Lacerda DC, Hirth CG

Tuberculous myositis in a patient with ankylosing spondylitis treated with adalimumab.

Rheumatology international 2009 Sep;29;1381-4 — 2009 Sep — 1381-4