The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

III.b

Pneumorenal syndrome (w/wo ANCAs)

Publications

Kaaroud H, Oueslati I, Harzallah A, Ben Nacef I, Khiari K, Ben Hamida F

Benzylthiouracil induced ANCA associated glomerulonephritis in patients with graves' disease.

La Tunisie medicale 2015 Nov;93;696-701 — 2015 Nov — 696-701

Kaaroud H, Khiari K, Ben Moussa F, Barbouch S, Boussema E, Ben Maïz H

[Vasculitis with renal and pulmonary involvement in a patient receiving benzylthiouracil for Graves disease].

La Revue de medecine interne 2002 Oct;23;857-61 — 2002 Oct — 857-61