The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Pneumonitis (interstitial lung disease/ILD)
Publications
Chronic Pulmonary Silicone Embolism Related to Saline Breast Implants.
Annals of the American Thoracic Society 2016 Jan;13;139-41 — 2016 Jan — 139-41
Increasing pulmonary infiltrates in a 72-year-old woman with metastatic breast cancer.
Chest 2014 Dec;146;e208-e211 — 2014 Dec — e208-e211
Chronic silicone embolism syndrome due to PIP breast implant leakage – a new entity?
Histopathology 2015 May;66;904-6 — 2015 May — 904-6
Autoimmune/inflammatory syndrome induced by adjuvants causing myositis and pulmonary fibrosis.
The Israel Medical Association journal : IMAJ 2013 Nov;15;720-1 — 2013 Nov — 720-1
Paredes Vila S, Gonzalez Barcala FJ, Suarez Antelo J, Moldes Rodriguez M, Abdulkader Nallib I, Valdes Cuadrado L
Pneumonitis caused by silicone gel following breast implant rupture.
Irish journal of medical science 2010 Mar;179;141-5 — 2010 Mar — 141-5
[Interstitial pneumonia associated with human adjuvant disease which developed 30 years after silicone augmentation mammoplasty].
Nihon Kyobu Shikkan Gakkai zasshi 1997 Oct;35;1093-8 — 1997 Oct — 1093-8