The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLII.d

Alveolar hemorrhage, diffuse (ANCA-positive/-related)

Publications

Pandey S, Kushwaha RS, Mehndiratta P, Mehndiratta MM

Carbimazole induced ANCA positive vasculitis.

The Journal of the Association of Physicians of India 2008 Oct;56;801-3 — 2008 Oct — 801-3

Calañas-Continente A, Espinosa M, Manzano-García G, Santamaría R, Lopez-Rubio F, Aljama P

Necrotizing glomerulonephritis and pulmonary hemorrhage associated with carbimazole therapy.

Thyroid : official journal of the American Thyroid Association 2005 Mar;15;286-8 — 2005 Mar — 286-8