The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.a

Pneumonitis (ILD)

Publications

Fernández AB, Karas RH, Alsheikh-Ali AA, Thompson PD

Statins and interstitial lung disease: a systematic review of the literature and of food and drug administration adverse event reports.

Chest 2008 Oct;134;824-30 — 2008 Oct — 824-30

Veyrac G, Cellerin L, Jolliet P

[A case of interstitial lung disease with atorvastatin (Tahor) and a review of the literature about these effects observed under statins].

Therapie 2006 Jan-Feb;61;57-67 — 2006 Jan-Feb — 57-67