The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.s

Vasculitis, pulmonary (w/wo AH), extrapulmonary, systemic: ANCA-positive

Publications

Kaaroud H, Oueslati I, Harzallah A, Ben Nacef I, Khiari K, Ben Hamida F

Benzylthiouracil induced ANCA associated glomerulonephritis in patients with graves' disease.

La Tunisie medicale. 2015;93(11):696-701

Baili L, Aydi Z, Daoud F, Ben Dhaou B, Boussema E, Kochbati S, Boussema F

[Benzylthiouracil induced ANCA-positive vasculitis].

La Tunisie medicale. 2014;92(6):428-30

Chebbi W, Zantour B, Alaya W, Belhadjali H, Sfar MH

[Benzylthiouracil-induced antineutrophil cytoplasmic antibody-associated cutaneous vasculitis: a case report and literature review].

La Revue de medecine interne. 2013;34(9):561-4

Trimeche Ajmi S, Braham R, Toumi S, Chadli Chaieb M, Maaroufi A, Ach K, Chaieb L

Benzylthiouracil-induced glomerulonephritis.

Case reports in medicine. 2009;2009:687285

Frigui M, Kechaou M, Haddouk S, Masmoudi A, Kaddour N, Masmoudi H, Turki H, Bahloul Z

[Benzylthiouracil induced ANCA-positive vasculitis: study of three cases and review of the literature].

Annales d'endocrinologie. 2008;69(6):517-22