The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LIX.e

Pneumocystis jiroveci pneumonia

Publications

Al Sona M, Al Battah H, Salama A, Alweis R

Fatal Pneumocystis jirovecii Pneumonia in a Patient on Adalimumab: A Case Report.

American journal of therapeutics 2019 Dec 17;; — 2019 Dec 17

Desales AL, Mendez-Navarro J, Méndez-Tovar LJ, Ortiz-Olvera NX, Cullen G, Ocampo J, Lemus W, Tun AE, Mayoral-Zavala A, Dehesa-Violante M

Pneumocystosis in a patient with Crohn's disease treated with combination therapy with adalimumab.

Journal of Crohn's & colitis 2012 May;6;483-7 — 2012 May — 483-7

Ikeuchi H, Umemoto A, Tsukida M, Sakurai N, Maeshima A, Kuroiwa T, Hiromura K, Nojima Y

[Pneumocystis pneumonia developed in two patients with rheumatoid arthritis during treatment of adalimumab].

Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 2011;34;420-5 — 2011 — 420-5

Koike T, Harigai M, Ishiguro N, Inokuma S, Takei S, Takeuchi T, Yamanaka H, Tanaka Y

Safety and effectiveness of adalimumab in Japanese rheumatoid arthritis patients: postmarketing surveillance report of the first 3,000 patients.

Modern rheumatology 2012 Aug;22;498-508 — 2012 Aug — 498-508

Kalyoncu U, Karadag O, Akdogan A, Kisacik B, Erman M, Erguven S, Ertenli AI

Pneumocystis carinii pneumonia in a rheumatoid arthritis patient treated with adalimumab.

Scandinavian journal of infectious diseases 2007;39;475-8 — 2007 — 475-8