The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Silicone pleural effusion
Publications
Silicone pleural effusion due to iatrogenic breast implant rupture.
Southern medical journal 1993 May;86;570-1 — 1993 May — 570-1
Silicone migration to the pleural space associated with silicone-gel augmentation mammaplasty.
Annals of plastic surgery 1994 Jun;32;645-7 — 1994 Jun — 645-7