The Drug-Induced Respiratory Disease Website and App

Breast implants - Augmentation mammaplasty (w/wo evidence for leakage/rupture)

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

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Silicone pleural nodules - Pleural siliconomas

Publications

Tanaka T, Tao H, Hayashi T, Yoshiyama K, Furukawa M, Yoshida K, Okabe K

Disseminated Pleural Siliconoma Mimicking Malignant Pleural Mesothelioma.

The Annals of thoracic surgery. 2015;100(6):2339-40

Levine RL, Allen TC, Cartwright J Jr, Cagle PT

Silicone thorax due to a ruptured breast implant.

Chest. 2005;127(5):1854-7