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XLIX.z

XLIX - Systemic/Distant conditions, syndromes and reactions

ANCA positivity. Subclinical or with clinical manifestations

Last update 02/04/2026

Antineutrophil cytoplamic antibodies (ANCA). More often p- than c-ANCA. Exact typing and target antigen determination are important. Polyspecificty and the presence of anti-HNE Ab are suggestive of the drug etiology. Subclinical organ damage or dysfuction should be investigated.

Causative drugs

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases