The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.o

Vascultis (pulmonary, extrathoracic or systemic)-ANCA status unknown or negative)

Publications

Cestelli V, Spinella A, Campomori F, Esposito C, Ciaffi S, Sandri G, Ferri C

Large Vessel Vasculitis Occurring in Rheumatoid Arthritis Patient under Anti-TNF Therapy.

Case reports in medicine 2014;2014;624184 — 2014 — 624184

Sokumbi O, Wetter DA, Makol A, Warrington KJ

Vasculitis associated with tumor necrosis factor-? inhibitors.

Mayo Clinic proceedings 2012 Aug;87;739-45 — 2012 Aug — 739-45