The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.a

Pneumonitis (ILD)

Publications

Numata T, Hida N, Yazaki K, Arai N, Ota K, Yanai H, Endo T

Seasonal Influenza Vaccine-induced Pneumonitis Presenting with Multiple Pulmonary Nodules.

Internal medicine (Tokyo, Japan) 2018 Mar 01;57;707-711 — 2018 Mar 01 — 707-711

Watanabe S, Waseda Y, Takato H, Inuzuka K, Katayama N, Kasahara K, Fujimura M

Influenza vaccine-induced interstitial lung disease.

The European respiratory journal 2013 Feb;41;474-7 — 2013 Feb — 474-7

Johnston SD, Kempston A, Robinson TJ

Pneumonitis secondary to the influenza vaccine.

Postgraduate medical journal 1998 Sep;74;541-2 — 1998 Sep — 541-2