The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Pleural/pericardial effusion, ANA positive (DI lupus)
Publications
Diverse patterns of anti-TNF-?-induced lupus: case series and review of the literature.
Clinical rheumatology 2018 Feb;37;563-568 — 2018 Feb — 563-568
Adalimumab-induced lupus serositis.
BMJ case reports 2015 Mar 04;2015; — 2015 Mar 04
Puertas-Abreu E, Polanco ER, Azocar M, Mundarain LA, Nuñez-Sotelo CM, Montaño R, Vivas FH, Noguera ZT, Marín F, Bellorin O, Rivas JG, Toro E, Benzaquen E, Rauseo M, Gutiérrez González LA,
Onset of lupus like syndrome in patients with spondyloarthritis treated with anti-TNF-?.
International archives of medicine 2012 Feb 15;5;7 — 2012 Feb 15 — 7
Lupus-like syndrome attributable to anti-tumor necrosis factor alpha therapy in 14 patients during an 8-year period at Mayo Clinic.
Mayo Clinic proceedings 2009 Nov;84;979-84 — 2009 Nov — 979-84
Ramos-Casals M, Brito-Zerón P, Muñoz S, Soria N, Galiana D, Bertolaccini L, Cuadrado MJ, Khamashta MA
Autoimmune diseases induced by TNF-targeted therapies: analysis of 233 cases.
Medicine 2007 Jul;86;242-51 — 2007 Jul — 242-51
Drug-induced systemic lupus erythematosus and TNF-alpha blockers.
Lancet (London, England) 2002 Aug 24;360;646 — 2002 Aug 24 — 646