The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIX.d

Lupus - Lupus syndrome (see also Vd)

Publications

Tetikkurt C, Yuruyen M, Tetikkurt S, Bayar N, Ozdemir I

Propylthiouracil-induced lupus-like or vasculitis syndrome.

Multidisciplinary respiratory medicine 2012 Jul 17;7;14 — 2012 Jul 17 — 14

Wu R, Li R

Propylthiouracil-induced autoimmune syndromes: 11 case report.

Rheumatology international 2012 Mar;32;679-81 — 2012 Mar — 679-81

Aloush V, Litinsky I, Caspi D, Elkayam O

Propylthiouracil-induced autoimmune syndromes: two distinct clinical presentations with different course and management.

Seminars in arthritis and rheumatism 2006 Aug;36;4-9 — 2006 Aug — 4-9

Pillinger MH, Staud R

Propylthiouracil and antineutrophil cytoplasmic antibody associated vasculitis: the detective finds a clue.

Seminars in arthritis and rheumatism 2006 Aug;36;1-3 — 2006 Aug — 1-3