The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLV.b

Eosinophilic pleural effusion

Publications

Sen N, Ermis H, Karatasli M, Habesoglu MA, Eyuboglu FO

Propylthiouracil-associated eosinophilic pleural effusion: a case report.

Respiration; international review of thoracic diseases 2007;74;703-5 — 2007 — 703-5

Middleton KL, Santella R, Couser JI

Eosinophilic pleuritis due to propylthiouracil.

Chest 1993 Mar;103;955-6 — 1993 Mar — 955-6