The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Path: Delayed Alveolar Injury with Delayed Epithelialization (DAIDE)
Publications
Rubin J, Chiu ML, Mino-Kenudson M, Sharma A, Witkin AS, Moschovis PP, Vogel Y, Shelton K, Crowley J, Raz Y
ARDS With Pneumothorax in a Young Adult.
Chest. 2022;161(2):e111-e116
Trimethoprim-Sulfamethoxazole-associated Fulminant Respiratory Failure in Children and Young Adults.
American journal of respiratory and critical care medicine. 2021;203(7):918-921
Taylor MS, Chivukula RR, Myers LC, Jeck WR, Waghray A, Tata PR, Selig MK, O'Donnell WJ, Farver CF, Thompson BT, Rajagopal J, Kradin RL
A Conserved Distal Lung Regenerative Pathway in Acute Lung Injury.
The American journal of pathology. 2018;188(5):1149-1160