The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIX.b

Antiphospholipid antibodies w/wo the APL syndrome

Publications

Kato M, Oiso N, Nozaki Y, Inoue A, Hosono Y, Funauchi M, Mimori T, Matsumura I, Kawada A

Antitumor necrosis factor alpha inhibitor-induced dermatomyositis and interstitial lung disease with anti-PL12 autoantibody: signs of antisynthetase syndrome.

The Journal of dermatology 2014 Nov;41;1034-6 — 2014 Nov — 1034-6

Vereckei E, Kriván G, Réti M, Szodoray P, Poór G, Kiss E

Anti-TNF-alpha-induced anti-phospholipid syndrome manifested as necrotizing vasculitis.

Scandinavian journal of rheumatology 2010 Mar;39;175-7 — 2010 Mar — 175-7

Ramos-Casals M, Brito-Zerón P, Soto MJ, Cuadrado MJ, Khamashta MA

Autoimmune diseases induced by TNF-targeted therapies.

Best practice & research. Clinical rheumatology 2008 Oct;22;847-61 — 2008 Oct — 847-61