The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XV.y

Path: Respiratory bronchiolitis (w/wo the RB-ILD-pattern)

Publications

Vassallo R, Ryu JH

Smoking-related interstitial lung diseases.

Clinics in chest medicine. 2012;33(1):165-78

Tazelaar HD, Wright JL, Churg A

Desquamative interstitial pneumonia.

Histopathology. 2011;58(4):509-16

Portnoy J, Veraldi KL, Schwarz MI, Cool CD, Curran-Everett D, Cherniack RM, King TE Jr, Brown KK

Respiratory bronchiolitis-interstitial lung disease: long-term outcome.

Chest. 2007;131(3):664-671

Craig PJ, Wells AU, Doffman S, Rassl D, Colby TV, Hansell DM, Du Bois RM, Nicholson AG

Desquamative interstitial pneumonia, respiratory bronchiolitis and their relationship to smoking.

Histopathology. 2004;45(3):275-82

Moon J, du Bois RM, Colby TV, Hansell DM, Nicholson AG

Clinical significance of respiratory bronchiolitis on open lung biopsy and its relationship to smoking related interstitial lung disease.

Thorax. 1999;54(11):1009-14