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The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.f

Anaphylaxis-Anaphylactoid reaction (can be fatal)

Publications

Swali R, Lee M

Anaphylactoid Reaction from Trimethoprim-Sulfamethoxazole with Subsequent T-wave Inversions in a Young Patient with Dermatomyositis.

The Journal of clinical and aesthetic dermatology. 2019;12(11):20-22

Schuster C, Wüthrich B

Anaphylactic drug reaction to celecoxib and sulfamethoxazole: cross reactivity or coincidence?

Allergy. 2003;58(10):1072

Arnold PA, Guglielmo BJ, Hollander H

Severe hypersensitivity reaction upon rechallenge with trimethoprim-sulfamethoxazole in a patient with AIDS.

Drug intelligence & clinical pharmacy. 1988;22(1):43-5

Johnson MP, Goodwin SD, Shands JW Jr

Trimethoprim-sulfamethoxazole anaphylactoid reactions in patients with AIDS: case reports and literature review.

Pharmacotherapy. 1990;10(6):413-6