The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Sarcoid-like granulomatosis (endo-/extrathoracic)
Publications
Anti-TNF Induced Sarcoidosis-Like Disease in Rheumatoid Arthritis Patients: Review Cases from the RA UCLouvain Brussels Cohort.
Rheumatology and therapy 2022 Feb 08;; — 2022 Feb 08
Tumour necrosis factor (TNF) inhibitor-induced isolated pleural granulomas: a rare adverse effect.
BMJ case reports 2017 Jun 18;2017; — 2017 Jun 18
Sarcoidosis associated with infliximab therapy in ulcerative colitis: A case report.
Medicine 2017 Mar;96;e6156 — 2017 Mar — e6156
[Sarcoïdosis and anti-TNF: a paradoxical class effect? Analysis of the French Pharmacovigilance system database and literature review].
Therapie 2011 Mar-Apr;66;149-54 — 2011 Mar-Apr — 149-54
Daïen CI, Monnier A, Claudepierre P, Constantin A, Eschard JP, Houvenagel E, Samimi M, Pavy S, Pertuiset E, Toussirot E, Combe B, Morel J,
Sarcoid-like granulomatosis in patients treated with tumor necrosis factor blockers: 10 cases.
Rheumatology (Oxford, England) 2009 Aug;48;883-6 — 2009 Aug — 883-6