The Drug-Induced Respiratory Disease Website and App

I. Interstitial/parenchymal lung disease

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

I. Interstitial/parenchymal lung disease

I.e Acute eosinophilic pneumonia (AEP)

I. Interstitial/parenchymal lung disease

I.j Exogenous lipoid pneumonia (subacute, acute)

I. Interstitial/parenchymal lung disease

I.m ILD with a granulomatous component

I. Interstitial/parenchymal lung disease

I.s A mass or masses

I. Interstitial/parenchymal lung disease

I.t Pneumoconiosis (silicosis, talcosis...)

II. Pulmonary edema - Acute lung injury - ARDS

II.a Pulmonary edema, noncardiogenic (NCPE)

II. Pulmonary edema - Acute lung injury - ARDS

II.b ARDS - Acute lung injury

III. Pulmonary/alveolar./airway hemorrhage/bleeding

III.a Alveolar hemorrhage (AH), diffuse AH (DAH)

IV. Airway involvement

IV.a Bronchospasm - Wheezing - Asthma

IV. Airway involvement

IV.f Severe or catastrophic bronchospasm or asthma attack (can be fatal)

IV. Airway involvement

IV.g Cough syncope

V. Pleural and/or pericardial involvement

V.f Pneumothorax

V. Pleural and/or pericardial involvement

V.q Empyema

V. Pleural and/or pericardial involvement

V.ab Pneumothorax, bilateral

VI. Pulmonary vasculopathy

VI.b Pulmonary arterial hypertension

VI. Pulmonary vasculopathy

VI.c Pulmonary veno-occlusive disease

VI. Pulmonary vasculopathy

VI.g Foreign body pulmonary vasculopathy (Excipient lung disease)

VI. Pulmonary vasculopathy

VI.i Acute pulmonary hypertension

VI. Pulmonary vasculopathy

VI.j Mercury pulmonary embolism

VI. Pulmonary vasculopathy

VI.r Septic pulmonary embolism

VI. Pulmonary vasculopathy

VI.t Pulmonary artery aneurysm(s)

VII. Mediastinal involvement

VII.h Pneumomediastinum

VII. Mediastinal involvement

VII.i Mediastinitis

VIII. Central-large-upper airway (incl. pharyngeal-nasal) involvement

VIII.c Upper airway obstruction other than angioedema or hematoma

VIII. Central-large-upper airway (incl. pharyngeal-nasal) involvement

VIII.d Thermal (burns, frostbite), chemical or caustic injury on the face, mouth, tongue, pharynx or upper airway

VIII. Central-large-upper airway (incl. pharyngeal-nasal) involvement

VIII.ai Nasal, palatal and/or pharyngeal pathology

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.a Diaphragm/inspiratory muscle weakness/paralysis (w/wo ARF)

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.s Botulism (foodborne-, wound-)

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.ah Acute myelopathy (can cause ARF)

X. Systemic/Distant conditions, syndromes and reactions

X.m Vascultis (pulmonary, extrathoracic or systemic)-ANCA status unknown or negative)

X. Systemic/Distant conditions, syndromes and reactions

X.u Multiple organ dysfunction/failure (MODS/MOF)

X. Systemic/Distant conditions, syndromes and reactions

X.ac Anti-GBM antibody disease (Goodpasture-like or flare of preexisting GS)

X. Systemic/Distant conditions, syndromes and reactions

X.bb Foreign body (talc, cornstarch) retinopathy

XI. Miscellaneous

XI.b Chest pain (acute or subacute), lone or prominent

XI. Miscellaneous

XI.g Aspiration, aspiration pneumonia (w/wo demonstrable pharyngeal dysmotility)

XI. Miscellaneous

XI.m Pulmonary emphysema - Lung cysts or bullae

XI. Miscellaneous

XI.r Death following exposure or poisoning

XII. Cardiovascular involvement / toxicity

XII.g Coronary artery disease (acute) - Myocardial ischemia/infarction

XII. Cardiovascular involvement / toxicity

XII.i Endocarditis (infective)

XII. Cardiovascular involvement / toxicity

XII.v Hypertrophic cardiomyopathy

XV. Pathology

XV.q Path: Foreign body deposits/granulomatous reaction

XV. Pathology

XV.s Path: Pneumoconiosis (silicosis, talcosis, talcoma)

XV. Pathology

XV.v Path: Micronodular organizing pneumonia/BOOP

XV. Pathology

XV.ag Path: Foreign body embolism, microangiopathy, vasculopathy

XV. Pathology

XV.al Path: Pulmonary hypertension incl. angiomatoid vasculopathy

XVI. Imaging

XVI.d Imaging: Alveolar opacities or haze with a batwing or butterfly distribution

XVI. Imaging

XVI.u Imaging: A miliary pattern (diffuse random micronodules)

XVI. Imaging

XVI.v Imaging: Centrilobular micronodules (can be diffuse)

XVI. Imaging

XVI.ab Imaging: Cavitating/cavitary lung nodule, mass or nodules (see also Iq, XIs, XIIi, XVIaa and XVIIp)

XVI. Imaging

XVI.ae Imaging: A pattern similar to pneumoconiotic progressive massive fibrosis (PMF)

XVI. Imaging

XVI.af Imaging: Lung cysts or bullae (see also XVI ah/bf)

XVI. Imaging

XVI.ai Imaging: A 'tree-in-bud' pattern

XVII. Infections & related conditions

XVII.a Respiratory tract infection incl. pneumonia

XVII. Infections & related conditions

XVII.b Opportunistic pulmonary/systemic infections

XVII. Infections & related conditions

XVII.g Tuberculosis (pulmonary, pulmonary, extrapulmonary or disseminated). Reactivation or de novo

XVII. Infections & related conditions

XVII.p Lung abscess/abscesses (see also VIr)

XVII. Infections & related conditions

XVII.s Sternoclavicular septic arthritis

XVII. Infections & related conditions

XVII.u Epidural abscess

XVII. Infections & related conditions

XVII.al Osteomyelitis (notably of thoracic bones)

XVIII. Distinctive patterns - 'Eye-catchers'

XVIII.t Eye catcher: Purpuric/Ecchymotic/Cyanotic lesions of the earlobes and/or nose

XVIII. Distinctive patterns - 'Eye-catchers'

XVIII.u Eye catcher: Talc retinopathy

XVIII. Distinctive patterns - 'Eye-catchers'

XVIII.x Eye catcher: A batwing pattern on imaging

V. Pleural and/or pericardial involvement

V.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

VI. Pulmonary vasculopathy

VI.g Foreign body pulmonary vasculopathy (Excipient lung disease)

X. Systemic/Distant conditions, syndromes and reactions

X.q Systemic inflammatory response

X. Systemic/Distant conditions, syndromes and reactions

X.s Vasculitis, pulmonary (w/wo AH), extrapulmonary, systemic: ANCA-positive

XV. Pathology

XV.q Path: Foreign body deposits/granulomatous reaction

XV. Pathology

XV.ag Path: Foreign body embolism, microangiopathy, vasculopathy

XV. Pathology

XV.bz Path: Hydrophilic polymer emboli

XVI. Imaging

XVI.w Imaging: Lung nodule or nodules

XVI. Imaging

XVI.ab Imaging: Cavitating/cavitary lung nodule, mass or nodules (see also Iq, XIs, XIIi, XVIaa and XVIIp)

XVI. Imaging

XVI.an Imaging: Pleural effusion

VI. Pulmonary vasculopathy

VI.g Foreign body pulmonary vasculopathy (Excipient lung disease)

XV. Pathology

XV.q Path: Foreign body deposits/granulomatous reaction

XV. Pathology

XV.ag Path: Foreign body embolism, microangiopathy, vasculopathy

I. Interstitial/parenchymal lung disease

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

I. Interstitial/parenchymal lung disease

I.d Organizing pneumonia pattern (an area or areas of consolidation on imaging)

I. Interstitial/parenchymal lung disease

I.e Acute eosinophilic pneumonia (AEP)

I. Interstitial/parenchymal lung disease

I.g Pulmonary fibrosis

I. Interstitial/parenchymal lung disease

I.m ILD with a granulomatous component

I. Interstitial/parenchymal lung disease

I.t Pneumoconiosis (silicosis, talcosis...)

II. Pulmonary edema - Acute lung injury - ARDS

II.a Pulmonary edema, noncardiogenic (NCPE)

IV. Airway involvement

IV.a Bronchospasm - Wheezing - Asthma

IV. Airway involvement

IV.f Severe or catastrophic bronchospasm or asthma attack (can be fatal)

IV. Airway involvement

IV.i Foreign body aspiration bronchiolitis

VI. Pulmonary vasculopathy

VI.b Pulmonary arterial hypertension

VI. Pulmonary vasculopathy

VI.e Fat/oil embolism - The FES embolism syndrome

VI. Pulmonary vasculopathy

VI.g Foreign body pulmonary vasculopathy (Excipient lung disease)

X. Systemic/Distant conditions, syndromes and reactions

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

X. Systemic/Distant conditions, syndromes and reactions

X.g Hypersensitivity reaction (may manifest with fever and/or skin, throat or airway involvement)

X. Systemic/Distant conditions, syndromes and reactions

X.u Multiple organ dysfunction/failure (MODS/MOF)

X. Systemic/Distant conditions, syndromes and reactions

X.bh Protracted, prolonged anaphylaxis

XI. Miscellaneous

XI.d Metabolic acidosis (incl. lactic acidosis/-gap). May cause hyperpnea/dyspnea

XII. Cardiovascular involvement / toxicity

XII.n Cardiovascular collapse - Cardiogenic shock - Hypotension

XV. Pathology

XV.q Path: Foreign body deposits/granulomatous reaction

XV. Pathology

XV.ae Path: Lipid/fat embolism (see also VIe)

XVI. Imaging

XVI.q Imaging: A pattern similar/consistent to/with IPF

XVI. Imaging

XVI.v Imaging: Centrilobular micronodules (can be diffuse)

VI. Pulmonary vasculopathy

VI.b Pulmonary arterial hypertension

VI. Pulmonary vasculopathy

VI.e Fat/oil embolism - The FES embolism syndrome

VI. Pulmonary vasculopathy

VI.g Foreign body pulmonary vasculopathy (Excipient lung disease)

XV. Pathology

XV.ag Path: Foreign body embolism, microangiopathy, vasculopathy

I. Interstitial/parenchymal lung disease

I.b Pneumonitis (interstitial lung disease/ILD)

I. Interstitial/parenchymal lung disease

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

I. Interstitial/parenchymal lung disease

I.d Organizing pneumonia pattern (an area or areas of consolidation on imaging)

I. Interstitial/parenchymal lung disease

I.e Acute eosinophilic pneumonia (AEP)

I. Interstitial/parenchymal lung disease

I.m ILD with a granulomatous component

II. Pulmonary edema - Acute lung injury - ARDS

II.a Pulmonary edema, noncardiogenic (NCPE)

II. Pulmonary edema - Acute lung injury - ARDS

II.b ARDS - Acute lung injury

II. Pulmonary edema - Acute lung injury - ARDS

II.d Pulmonary edema, cardiogenic

II. Pulmonary edema - Acute lung injury - ARDS

II.i Flash (fulminate) pulmonary edema

III. Pulmonary/alveolar./airway hemorrhage/bleeding

III.a Alveolar hemorrhage (AH), diffuse AH (DAH)

IV. Airway involvement

IV.a Bronchospasm - Wheezing - Asthma

IV. Airway involvement

IV.f Severe or catastrophic bronchospasm or asthma attack (can be fatal)

IV. Airway involvement

IV.k Bronchiectasis

V. Pleural and/or pericardial involvement

V.f Pneumothorax

VI. Pulmonary vasculopathy

VI.b Pulmonary arterial hypertension

VI. Pulmonary vasculopathy

VI.g Foreign body pulmonary vasculopathy (Excipient lung disease)

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.d Respiratory failure from ventilatory depression (due to neuromuscular blockade/paralysis)

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.i Respiratory arrest - Apnea

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.s Botulism (foodborne-, wound-)

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.ad Parsonage-Turner amyotrophic neuralgia-like syndrome

XI. Miscellaneous

XI.g Aspiration, aspiration pneumonia (w/wo demonstrable pharyngeal dysmotility)

XI. Miscellaneous

XI.r Death following exposure or poisoning

XII. Cardiovascular involvement / toxicity

XII.f Cardiomyopathy (acute, subacute, chronic)

XII. Cardiovascular involvement / toxicity

XII.l Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)

XV. Pathology

XV.c Path: Organizing pneumonia (OP/BOOP) pattern (see also Id)

XV. Pathology

XV.s Path: Pneumoconiosis (silicosis, talcosis, talcoma)

XV. Pathology

XV.w Path: Pulmonary edema (see also II/IIa)

XVI. Imaging

XVI.d Imaging: Alveolar opacities or haze with a batwing or butterfly distribution

XVII. Infections & related conditions

XVII.b Opportunistic pulmonary/systemic infections

XXIV. Veterinary medicine

XXIV.c Veterinary: Pulmonary edema

I. Interstitial/parenchymal lung disease

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

I. Interstitial/parenchymal lung disease

I.t Pneumoconiosis (silicosis, talcosis...)

IV. Airway involvement

IV.n Obstructive airway dysfunction (see also IVc, XVx)

V. Pleural and/or pericardial involvement

V.f Pneumothorax

VI. Pulmonary vasculopathy

VI.b Pulmonary arterial hypertension

VI. Pulmonary vasculopathy

VI.g Foreign body pulmonary vasculopathy (Excipient lung disease)

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.k Trismus (lockjaw)

X. Systemic/Distant conditions, syndromes and reactions

X.m Vascultis (pulmonary, extrathoracic or systemic)-ANCA status unknown or negative)

X. Systemic/Distant conditions, syndromes and reactions

X.bb Foreign body (talc, cornstarch) retinopathy

XI. Miscellaneous

XI.b Chest pain (acute or subacute), lone or prominent

XI. Miscellaneous

XI.m Pulmonary emphysema - Lung cysts or bullae

XII. Cardiovascular involvement / toxicity

XII.g Coronary artery disease (acute) - Myocardial ischemia/infarction

XV. Pathology

XV.b Path: Eosinophilic pneumonia (subacute or acute) (see also Ic)

XV. Pathology

XV.q Path: Foreign body deposits/granulomatous reaction

I. Interstitial/parenchymal lung disease

I.t Pneumoconiosis (silicosis, talcosis...)

II. Pulmonary edema - Acute lung injury - ARDS

II.a Pulmonary edema, noncardiogenic (NCPE)

II. Pulmonary edema - Acute lung injury - ARDS

II.b ARDS - Acute lung injury

II. Pulmonary edema - Acute lung injury - ARDS

II.f Hypoxemia, low oxygen saturation (may occur in isolation)

VI. Pulmonary vasculopathy

VI.b Pulmonary arterial hypertension

VI. Pulmonary vasculopathy

VI.g Foreign body pulmonary vasculopathy (Excipient lung disease)

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.c Chest wall muscle rigidity - Stiff/wooden chest

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.d Respiratory failure from ventilatory depression (due to neuromuscular blockade/paralysis)

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.e Disordered breathing pattern incl. Cheyne-Stokes respiration

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.i Respiratory arrest - Apnea

XI. Miscellaneous

XI.r Death following exposure or poisoning

XII. Cardiovascular involvement / toxicity

XII.e Takotsubo (stress) cardiomyopathy

XII. Cardiovascular involvement / toxicity

XII.f Cardiomyopathy (acute, subacute, chronic)

XII. Cardiovascular involvement / toxicity

XII.l Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)

XII. Cardiovascular involvement / toxicity

XII.p QTc prolongation

XII. Cardiovascular involvement / toxicity

XII.t Torsades de pointe

XII. Cardiovascular involvement / toxicity

XII.bo Right ventricular dysfunction.failure

VI. Pulmonary vasculopathy

VI.g Foreign body pulmonary vasculopathy (Excipient lung disease)

XV. Pathology

XV.ag Path: Foreign body embolism, microangiopathy, vasculopathy

VI. Pulmonary vasculopathy

VI.g Foreign body pulmonary vasculopathy (Excipient lung disease)

I. Interstitial/parenchymal lung disease

I.d Organizing pneumonia pattern (an area or areas of consolidation on imaging)

I. Interstitial/parenchymal lung disease

I.t Pneumoconiosis (silicosis, talcosis...)

II. Pulmonary edema - Acute lung injury - ARDS

II.b ARDS - Acute lung injury

II. Pulmonary edema - Acute lung injury - ARDS

II.f Hypoxemia, low oxygen saturation (may occur in isolation)

IV. Airway involvement

IV.c Obliterative bronchiolitis (a pattern consistent with) (see also IVn, XVx)

IV. Airway involvement

IV.i Foreign body aspiration bronchiolitis

IV. Airway involvement

IV.m Bronchial stenosis/stricture

V. Pleural and/or pericardial involvement

V.c Pleural thickening - Fibrothorax

V. Pleural and/or pericardial involvement

V.r Pleural mass or masses

VI. Pulmonary vasculopathy

VI.b Pulmonary arterial hypertension

VI. Pulmonary vasculopathy

VI.g Foreign body pulmonary vasculopathy (Excipient lung disease)

VII. Mediastinal involvement

VII.f An enlarged or dense thymus

VII. Mediastinal involvement

VII.n Mediastinal talcoma

X. Systemic/Distant conditions, syndromes and reactions

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

XI. Miscellaneous

XI.b Chest pain (acute or subacute), lone or prominent

XI. Miscellaneous

XI.u Chest pressure/discomfort

XV. Pathology

XV.e Path: ILD with a granulomatous component (see also Im)

XV. Pathology

XV.q Path: Foreign body deposits/granulomatous reaction

XV. Pathology

XV.s Path: Pneumoconiosis (silicosis, talcosis, talcoma)

XV. Pathology

XV.ag Path: Foreign body embolism, microangiopathy, vasculopathy

XV. Pathology

XV.da Path: Birefringent particles in lung tissue and/or cells

XVI. Imaging

XVI.w Imaging: Lung nodule or nodules

XVI. Imaging

XVI.ae Imaging: A pattern similar to pneumoconiotic progressive massive fibrosis (PMF)

XVI. Imaging

XVI.bm Imaging: Avid pleural uptake on PET-scan

XVIII. Distinctive patterns - 'Eye-catchers'

XVIII.i Eye-catcher: Tracer-avid pleural area or areas on PET-CT

XIX. Cytological, biochemical features of/in BAL, pleural fluid or FNA

XIX.k BAL: Talc crystals in macrophages or lying free in BALF