The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
Publications
Loeffler's syndrome; occurrence in two patients treated with penicillin in oil and wax.
Journal of the American Medical Association 1949 Sep 03;141;21 — 1949 Sep 03 — 21
The use of beclomethasone diproprionate inhaler complicated by the development of an eosinophilic pneumonia reaction.
Annals of allergy 1977 Aug;39;133-6 — 1977 Aug — 133-6