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The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XV.q

Path: Foreign body deposits/granulomatous reaction

Publications

Fanggiday JC, Rouse RW, Collard SM, de Haas MJ, de Klerk JM

Persistent Inflammation in Pulmonary Granuloma 48 Years after Talcage Pleurodesis, Detected by FDG-PET/CT.

Case reports in medicine. 2012;2012:686153

Hemdan Abdalla AM, White D

A 29-year-old woman with a remote history of osteosarcoma and positron emission tomography-positive pleurally based masses. Talcomas secondary to prior talc pleurodesis.

Chest. 2008;134(3):640-643

Conen D, Schilter D, Bubendorf L, Brutsche MH, Leuppi JD

Interstitial lung disease in an intravenous drug user.

Respiration; international review of thoracic diseases. 2003;70(1):101-3

Nan DN, Fernández-Ayala M, Iglesias L, García-Palomo D, Parra JA, Fariñas MC

Talc granulomatosis. A differential diagnosis of interstitial lung disease in HIV patients.

Chest. 2000;118(1):258-60