The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Path: Foreign body deposits/granulomatous reaction
Publications
Persistent Inflammation in Pulmonary Granuloma 48 Years after Talcage Pleurodesis, Detected by FDG-PET/CT.
Case reports in medicine 2012;2012;686153 — 2012 — 686153
A 29-year-old woman with a remote history of osteosarcoma and positron emission tomography-positive pleurally based masses. Talcomas secondary to prior talc pleurodesis.
Chest 2008 Sep;134;640-643 — 2008 Sep — 640-643
Interstitial lung disease in an intravenous drug user.
Respiration; international review of thoracic diseases 2003 Jan-Feb;70;101-3 — 2003 Jan-Feb — 101-3
Talc granulomatosis. A differential diagnosis of interstitial lung disease in HIV patients.
Chest 2000 Jul;118;258-60 — 2000 Jul — 258-60