The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

VII.g

Foreign body pulmonary vasculopathy (Excipient lung disease)

Publications

Fields TA, McCall SJ, Reams BD, Roggli VL, Palmer SM, Howell DN

Pulmonary embolization of microcrystalline cellulose in a lung transplant recipient.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2005 May;24;624-7 — 2005 May — 624-7

Farber H, Glauser FL

The effect of oral hydralazine on the pulmonary hemodynamics of patients with pulmonary foreign body granulomatosis.

Chest 1982 Dec;82;708-12 — 1982 Dec — 708-12

Zeltner TB, Nussbaumer U, Rudin O, Zimmermann A

Unusual pulmonary vascular lesions after intravenous injections of microcrystalline cellulose. A complication of pentazocine tablet abuse.

Virchows Archiv. A, Pathological anatomy and histology 1982;395;207-16 — 1982 — 207-16