Philippe Camus, M.D.

Dijon, France

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The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

VII.b

Pulmonary arterial hypertension

Publications

Hossein-Zadeh Z, Shuman MJ, Rapkiewicz A

Fatal Excipients: An Autopsy Case Series of Excipient Lung Disease.

The American journal of forensic medicine and pathology 2022 Mar 01;43;81-89 — 2022 Mar 01 — 81-89

Lemoine R, Dusmet M

Images in clinical medicine. Pulmonary granulomas in an intravenous drug user.

The New England journal of medicine 2000 Nov 02;343;1312 — 2000 Nov 02 — 1312

Arnett EN, Battle WE, Russo JV, Roberts WC

Intravenous injection of talc-containing drugs intended for oral use. A cause of pulmonary granulomatosis and pulmonary hypertension.

The American journal of medicine 1976 May 10;60;711-8 — 1976 May 10 — 711-8