The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

VI.g

Foreign body pulmonary vasculopathy (Excipient lung disease)

Publications

Cook RC, Fradet G, English JC, Soos J, Müller NL, Connolly TP, Levy RD

Recurrence of intravenous talc granulomatosis following single lung transplantation.

Canadian respiratory journal 1998 Nov-Dec;5;511-4 — 1998 Nov-Dec — 511-4

Waller BF, Brownlee WJ, Roberts WC

Self-induced pulmonary granulomatosis. A consequence of intravenous injection of drugs intended for oral use.

Chest 1980 Jul;78;90-4 — 1980 Jul — 90-4

Tomashefski JF, Hirsch CS

The pulmonary vascular lesions of intravenous drug abuse.

Human pathology 1980 Mar;11;133-45 — 1980 Mar — 133-45

Brown DG, Aguirre A, Weaver A

67Gallium scanning in talc-induced pulmonary granulomatosis.

Chest 1980 Apr;77;561-5 — 1980 Apr — 561-5

Schmidt RA, Glenny RW, Godwin JD, Hampson NB, Cantino ME, Reichenbach DD

Panlobular emphysema in young intravenous Ritalin abusers.

The American review of respiratory disease 1991 Mar;143;649-56 — 1991 Mar — 649-56