The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

VI.b

Pulmonary arterial hypertension

Foreign body vasculopathy should be investigated, even in buprenorphine users

Publications

Traclet J, Khouatra C, Piégay F, Turquier S, Zeghmar S, Mornex JF, Cordier JF, Cottin V

Pulmonary arterial hypertension in heroin users.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 2016;35(7):932-4

Ferrari E, Drai E, Taillan B, Talbodec A, Baudouy M, Morand P

[Pulmonary hypertension caused by talcoma in a couple of drug addicts].

Annales de cardiologie et d'angeiologie. 1995;44(1):14-5

Tomashefski JF Jr, Hirsch CS

The pulmonary vascular lesions of intravenous drug abuse.

Human pathology. 1980;11(2):133-45

Magnan A, Ottomani A, Garbe L, Arnaud A, Manelli JC

[Respiratory failure in a HIV seropositive heroin addict female].

Annales francaises d'anesthesie et de reanimation. 1991;10(1):74-6