The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Foreign body pulmonary vasculopathy (Excipient lung disease)
Publications
Intravenous injection of pharmaceutical tablets presenting as multiple pulmonary nodules and declining pulmonary function in an adolescent with cystic fibrosis.
Pediatrics. 2006;118(3):e924-8
Pulmonary granulomatous vasculitis induced by insoluble particulates: a case report.
Ultrastructural pathology. 2003;27(6):439-49
Embolized crospovidone (poly[N-vinyl-2-pyrrolidone]) in the lungs of intravenous drug users.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2003;16(4):286-92
Images in clinical medicine. Pulmonary granulomas in an intravenous drug user.
The New England journal of medicine. 2000;343(18):1312