The Drug-Induced Respiratory Disease Website and App

Talc (inhaled, sniffed, i.v., intrapleural)

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIX.f

Anaphylaxis-Anaphylactoid reaction (can be fatal)

Publications

Morota M, Tsuchiya T

Anaphylactic shock caused by talc pleurodesis performed for postoperative air leakage.

The Annals of thoracic surgery 2020 Jun 26;; — 2020 Jun 26

Inoue T, Ishida A, Nakamura M, Nishine H, Mineshita M, Miyazawa T

Talc pleurodesis for the management of malignant pleural effusions in Japan.

Internal medicine (Tokyo, Japan) 2013;52;1173-6 — 2013 — 1173-6