The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LI.g

Cardiomyopathy (acute, subacute, chronic)

Publications

Routsi C, Kolias S, Kaskarellis I, Politis P, Zervou M, Filippatos G, Roussos C

Acute cardiomyopathy and cardiogenic pulmonary edema after inhaled heroin use.

Acta anaesthesiologica Scandinavica 2007 Feb;51;262-4 — 2007 Feb — 262-4

Paranthaman SK, Khan F

Acute cardiomyopathy with recurrent pulmonary edema and hypotension following heroin overdosage.

Chest 1976 Jan;69;117-9 — 1976 Jan — 117-9