The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Path: Foreign body embolism, microangiopathy, vasculopathy
Publications
Diffuse talc granulomatosis in a patient with Crohn's disease.
American journal of respiratory and critical care medicine 2012 Oct 01;186;e11 — 2012 Oct 01 — e11
Intravascular Talcosis due to Intravenous Drug Use Is an Underrecognized Cause of Pulmonary Hypertension.
Pulmonary medicine 2012;2012;617531 — 2012 — 617531
ANGIOTHROMBOTIC PULMONARY HYPERTENSION IN ADDICTS. "BLUE VELVET" ADDICTION.
JAMA 1964 May 25;188;755-7 — 1964 May 25 — 755-7
Talc granulomatosis and angiothrombotic pulmonary hypertension in drug addicts.
Journal of the Canadian Association of Radiologists 1974 Jun;25;87-93 — 1974 Jun — 87-93