The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Bronchiectasis
Publications
Pulmonary complication of heroin intoxication. Aspiration pneumonia and diffuse bronchiectasis.
JAMA 1972 Feb 21;219;1051-3 — 1972 Feb 21 — 1051-3
Bronchiectasis following heroin-induced pulmonary edema. Rapid clearing of pulmonary infiltrates.
Chest 1976 Apr;69;552-5 — 1976 Apr — 552-5
Bronchiectasis: a cause of pulmonary symptoms in heroin addicts.
Respiration; international review of thoracic diseases 1979;37;232-7 — 1979 — 232-7