The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.n

ILD with a granulomatous component

Publications

Bishay A, Amchentsev A, Saleh A, Patel N, Travis W, Raoof S

A hitherto unreported pulmonary complication in an IV heroin user.

Chest 2008 Feb;133;549-51 — 2008 Feb — 549-51

Lemoine R, Dusmet M

Images in clinical medicine. Pulmonary granulomas in an intravenous drug user.

The New England journal of medicine 2000 Nov 02;343;1312 — 2000 Nov 02 — 1312