The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Foreign body pulmonary vasculopathy (Excipient lung disease)
Publications
Identification at autopsy of pulverized pills in lungs of a first-time methadone user.
Journal of forensic and legal medicine 2009 Nov;16;494-6 — 2009 Nov — 494-6
The pulmonary vascular lesions of intravenous drug abuse.
Human pathology 1980 Mar;11;133-45 — 1980 Mar — 133-45