The Drug-Induced Respiratory Disease Website and App

IV. Airway involvement

IV.d Cough (lone)

IV. Airway involvement

IV.g Cough syncope

V. Pleural and/or pericardial involvement

V.d Pleural/pericardial effusion, ANA positive (DI lupus)

VIII. Central-large-upper airway (incl. pharyngeal-nasal) involvement

VIII.a Angioedema (may cause UAO, asphyxia and death)

VIII. Central-large-upper airway (incl. pharyngeal-nasal) involvement

VIII.q Tongue involvement (edema, glossitis, hematoma)

VIII. Central-large-upper airway (incl. pharyngeal-nasal) involvement

VIII.y Sinonasal discharge, -blockage, -obstruction

VIII. Central-large-upper airway (incl. pharyngeal-nasal) involvement

VIII.am Hemilingual (angio)edema

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.q Obstructive sleep apnea

X. Systemic/Distant conditions, syndromes and reactions

X.d Lupus - Lupus syndrome (see also Vd)

X. Systemic/Distant conditions, syndromes and reactions

X.au Visceral angioedema (can cause relapsing abdominal pain)

XIII. Neoplastic conditions

XIII.a Lung cancer

XVI. Imaging

XVI.bu Imaging: Upper/central airway narrowing

XVIII. Distinctive patterns - 'Eye-catchers'

XVIII.f Eye-catcher: Tongue edema

VI. Pulmonary vasculopathy

VI.b Pulmonary arterial hypertension

XII. Cardiovascular involvement / toxicity

XII.b Valvular heart disease and/or dysfunction

XVI. Imaging

XVI.j Imaging: Wandering (migratory) pulmonary opacities

III. Pulmonary/alveolar/airway hemorrhage/bleeding

III.a Alveolar hemorrhage (AH), diffuse AH (DAH)

III. Pulmonary/alveolar/airway hemorrhage/bleeding

III.c Hemoptysis

III. Pulmonary/alveolar/airway hemorrhage/bleeding

III.e Pulmonary hematoma

III. Pulmonary/alveolar/airway hemorrhage/bleeding

III.k Epistaxis

IV. Airway involvement

IV.af Calcification of tracheobronchial cartilaginous rings

V. Pleural and/or pericardial involvement

V.e Hemothorax - Serosanguineous pleural effusion

V. Pleural and/or pericardial involvement

V.n Hemopericardium - Bloody pericardial effusion

VII. Mediastinal involvement

VII.g Hemomediastinum - Mediastinal hematoma

VIII. Central-large-upper airway (incl. pharyngeal-nasal) involvement

VIII.b Hematoma of/around central airway wall potentially causing UAO

VIII. Central-large-upper airway (incl. pharyngeal-nasal) involvement

VIII.u Vocal cord hematoma

VIII. Central-large-upper airway (incl. pharyngeal-nasal) involvement

VIII.v Retropharyngeal hematoma (may cause UAO)

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.x Thoracic epidural or spinal hematoma

XI. Miscellaneous

XI.k Esophageal hematoma (may cause chest pain and/or tracheal compression)

XI. Miscellaneous

XI.am Rectus abdominis hematoma

XII. Cardiovascular involvement / toxicity

XII.ar Calcification of the coronary artery walls or atheroma

XIX. Cytological, biochemical features of/in BAL, pleural fluid or FNA

XIX.d BAL: Gross or microscopic bleeding/hemorrhage

XIX. Cytological, biochemical features of/in BAL, pleural fluid or FNA

XIX.e BAL: Stainable iron in macrophages

XXIV. Veterinary medicine

XXIV.e Veterinary: Tracheal hemorrhage, stenosis, collapse

X. Systemic/Distant conditions, syndromes and reactions

X.a DRES syndrome - DRESS-like reaction

X. Systemic/Distant conditions, syndromes and reactions

X.b Antiphospholipid antibodies w/wo the APL syndrome

X. Systemic/Distant conditions, syndromes and reactions

X.y Subclinical ANA positivity

XVII. Infections & related conditions

XVII.w Hypogammaglobulinemia - Antibody deficiency

V. Pleural and/or pericardial involvement

V.b Eosinophilic pleural effusion

V. Pleural and/or pericardial involvement

V.f Pneumothorax

VI. Pulmonary vasculopathy

VI.y Pulmonary hypertension of the newborn (Persistent PHT)

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.e Disordered breathing pattern incl. Cheyne-Stokes respiration

I. Interstitial/parenchymal lung disease

I.af Chemical (toxic) pneumonitis

I. Interstitial/parenchymal lung disease

I.ao Pulmonary infiltrates

III. Pulmonary/alveolar/airway hemorrhage/bleeding

III.j Anti-GBM-related pneumorenal syndrome and DAH (Goodpasture) or flare of

IV. Airway involvement

IV.j Bronchiolitis (a clinical-imaging pattern suggestive of)

IV. Airway involvement

IV.n Obstructive airway dysfunction (see also IVc, XVx)

IV. Airway involvement

IV.q Reactive airway dysfunction syndrome (RADS)

IV. Airway involvement

IV.aj Airway hemorrhage on endoscopy

VIII. Central-large-upper airway (incl. pharyngeal-nasal) involvement

VIII.al Epiglottitis

VIII. Central-large-upper airway (incl. pharyngeal-nasal) involvement

VIII.ay Tracheal injury

XV. Pathology

XV.w Path: Pulmonary edema (see also II/IIa)

XVI. Imaging

XVI.v Imaging: Centrilobular micronodules (can be diffuse)

XVI. Imaging

XVI.ai Imaging: A 'tree-in-bud' pattern

I. Interstitial/parenchymal lung disease

I.b Pneumonitis (interstitial lung disease/ILD)

I. Interstitial/parenchymal lung disease

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

I. Interstitial/parenchymal lung disease

I.d Organizing pneumonia pattern (an area or areas of consolidation on imaging)

I. Interstitial/parenchymal lung disease

I.g Pulmonary fibrosis

I. Interstitial/parenchymal lung disease

I.l Diffuse alveolar damage (DAD) (see alsoo under IIb and XVf)

I. Interstitial/parenchymal lung disease

I.r An imaging pattern consistent with DIP

I. Interstitial/parenchymal lung disease

I.v Abnormal lung function/pulmonary physiology (PFTs) without necessarily imaging or clinical evidence

I. Interstitial/parenchymal lung disease

I.ax Chronic pneumonitis

II. Pulmonary edema - Acute lung injury - ARDS

II.b ARDS - Acute lung injury

II. Pulmonary edema - Acute lung injury - ARDS

II.j Transient pulmonary opacities/infiltrates (see also under Iav)

IV. Airway involvement

IV.ae Tracheobronchitis-like clinical pattern

V. Pleural and/or pericardial involvement

V.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

V. Pleural and/or pericardial involvement

V.i Pleuritis (can cause chest pain)

VI. Pulmonary vasculopathy

VI.d Pulmonary vasculitis or capillaritis

VII. Mediastinal involvement

VII.a Lymphadenopathy (intrathoracic)

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.i Respiratory arrest - Apnea

X. Systemic/Distant conditions, syndromes and reactions

X.e Autoimmunity-Autoimmune conditions (+ANA, +anti-ds-DNA, +ANCAs, other auto-Abs)

XI. Miscellaneous

XI.c Pleuritic chest pain

XI. Miscellaneous

XI.bn A restrictive lung function defect

XV. Pathology

XV.a Path: NSIP-cellular pattern (see also Ia, Ib)

XV. Pathology

XV.b Path: Eosinophilic pneumonia (subacute or acute) (see also Ic)

XV. Pathology

XV.c Path: Organizing pneumonia (OP/BOOP) pattern (see also Id)

XV. Pathology

XV.e Path: ILD with a granulomatous component (see also Im)

XV. Pathology

XV.f Path: Diffuse alveolar damage (DAD-pattern) (see also IL)

XV. Pathology

XV.h Path: NSIP-fibrotic pattern

XV. Pathology

XV.j Path: Pulmonary fibrosis (UIP-pattern)

XV. Pathology

XV.k Path: Desquamative interstitial pneumonia (DIP-pattern)

XV. Pathology

XV.x Path: Acute/subacute bronchiolitis (see also IVc, IVi)

XV. Pathology

XV.ac Path: Pulmonary vasculitis other than capillaritis

XV. Pathology

XV.af Path: Granulomatous pulmonary vasculitis

XV. Pathology

XV.bi Path: Giant-cell interstitial pneumonia (GIP)-pattern

XV. Pathology

XV.bl Path: Resolving alveolar damage

XVI. Imaging

XVI.b Imaging: Ground-glass opacities (GGO) / shadowing

XVI. Imaging

XVI.f Imaging: Bibasilar opacities/shadowing

XVI. Imaging

XVI.l Imaging: Peribronchovascular areas of consolidation

XVI. Imaging

XVI.bc Imaging: Intrathoracic lymph node enlargement

XVI. Imaging

XVI.bp Imaging: Reverse ventilation-perfusion mismatch

I. Interstitial/parenchymal lung disease

I.a Pneumonitis (ILD), acute and/or severe (may produce the ARDS pattern)