The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Thermal skin/dermal injury
Usually inflicted by self or schoolmate directing the freezing aerosol directly on skin
Publications
Salbutamol inhaler misuse resulting in skin burn.
The Journal of allergy and clinical immunology 2011 Jan;127;295 — 2011 Jan — 295
An unusual self inflicted burn in an asthmatic patient.
Burns : journal of the International Society for Burn Injuries 2003 Mar;29;191-2 — 2003 Mar — 191-2